METHODS AND APPARATUS FOR MONITORING CHRONIC DISEASE

The present invention discloses a method of monitoring chronic respiratory disease state of a patient, the method comprising: extracting, in a processor, for each of a plurality of monitoring sessions, a respiratory feature from a respiratory signal indicative of the patient's respiration during the monitoring session, the respiratory signal derived from at least one sensor; and computing, in a processor, a stability measure of the patient for a monitoring session, the stability measure representing an indication of a change point having occurred at the monitoring session in a statistical distribution of the respiratory feature, generating, by the processor, an output comprising an alert or presentation based on the stability measure, wherein the chronic respiratory disease state of the patient comprises Chronic Obstructive Pulmonary Disease or a cardio-pulmonary disorder.