RIBOFLAVIN FOR THE TREATMENT OF ISCHEMIC STROKE AND/OR OTHER GLUTAMATE EXCITOTOXICITY-ASSOCIATED DISEASES

The present invention relates to a combination therapy comprising the use of riboflavin and oxaloacetate. Specifically, it is directed to new compositions, pharmaceutical compositions, kits of parts and methods for treating ischemic stroke and/or other excitotoxicity-associated diseases. It further...

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Bibliographische Detailangaben
Hauptverfasser: BREA FLORIANI, JOSÉ MANUEL, CAMPOS PÉREZ, FRANCISCO, SOBRINO MOREIRAS, TOMÁS, LOZA GARCÍA, Mª ISABEL, CASTILLO SÁNCHEZ, JOSÉ
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a combination therapy comprising the use of riboflavin and oxaloacetate. Specifically, it is directed to new compositions, pharmaceutical compositions, kits of parts and methods for treating ischemic stroke and/or other excitotoxicity-associated diseases. It further relates to riboflavin for use in the therapeutic treatment of acute ischemic stroke by intravascular administration within the first twelve hours of symptom onset.