CRYSTALLINE FORM OF TAPENTADOL INTERMEDIATE

The present invention pertains to a crystalline and stable form of (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-(phenylmethoxy)benzenepropanamine, as well as to processes for its preparation, and its use in the preparation of tapentadol and pharmaceutically acceptable salts thereof.

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Bibliographische Detailangaben
Hauptverfasser: BERGANT SIMONCIC, Ana, SMIRNOVA, Elena, KLJAJIC, Alen
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention pertains to a crystalline and stable form of (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-(phenylmethoxy)benzenepropanamine, as well as to processes for its preparation, and its use in the preparation of tapentadol and pharmaceutically acceptable salts thereof.