SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

The invention provides a method for preparing a compound of formula (I):comprising contacting a compound of formula (Ia)or a compound of formula (Ic)with R1-L-NH2, in an organic solvent, in the presence of a base, under conditions as defined herein. Also provided are reaction intermediates involved...

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Bibliographische Detailangaben
Hauptverfasser: TORRES, Eduardo, PAPA, Patrick, HEGDE, Sayee, NORRIS, Stephen Tyson, CALABRESE, Andrew, Antony, DELGADO, Maria, Mercedes, HANSEN, Joshua, BAHMANYAR, Sogole, CORREA, Matthew, HUANG, Dehua, WHITEFIELD, Brandon, Wade, RAHEJA, Raj, CATHERS, Brian, Edwin, CASHION, Daniel, BENNETT, Brydon, LEFTHERIS, Katerina, MORTENSEN, Deborah, SAPIENZA, John, PARNES, Jason, PLANTEVIN-KRENITSKY, Veronique
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides a method for preparing a compound of formula (I):comprising contacting a compound of formula (Ia)or a compound of formula (Ic)with R1-L-NH2, in an organic solvent, in the presence of a base, under conditions as defined herein. Also provided are reaction intermediates involved in said method as defined herein.