ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS

The present invention relates to a compound represented by formula I:and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-co...

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Bibliographische Detailangaben
Hauptverfasser:	WANG, Bowei, PIO, Barbara, CHOBANIAN, Harry, BLIZZARD, Timothy, SZEWCZYK, Jason, W, PARKER, Dann, TIAN, Lili, LIN, Linus, S, HAGMANN, William, K, LI, Bing, LV, Ying, GUDE, Candido, DANG, Qun, BIJU, Purakkattle, HU, Bin, ZHANG, Zaihong, JOSIEN, Hubert, CUI, Mingxiang, CHEN, Zhengxia, DAI, Meibi, NARGUND, Ravi, P
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to a compound represented by formula I:and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.