STABLE EPISOMES BASED ON NON-INTEGRATIVE LENTIVIRAL VECTORS

The invention relates to non-intregrative lentiviral vectors and their use for the stable transgenesis of both dividing and no-dividing eukaryotic cells. The invention also provides methods for obtaining these vectors, the use of these vectors for the production of recombinant lentiviruses, and the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RAMÍREZ MARTÍNEZ, JUAN CARLOS, GARCÍA TORRALBA, AIDA, TORRES RUIZ, RAÚL
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to non-intregrative lentiviral vectors and their use for the stable transgenesis of both dividing and no-dividing eukaryotic cells. The invention also provides methods for obtaining these vectors, the use of these vectors for the production of recombinant lentiviruses, and the use of these recombinant lentiviruses for obtaining a cell able to stably produce a product of interest.