METHODS OF MEDIATING MACROPHAGE PHENOTYPES

Methods of inducing a polarization of macrophages. The method includes obtaining a blood fraction, fractionating the blood fraction to produce a blood fraction, and contacting the blood fraction with a source of macrophages. A blood fraction including platelet-poor plasma polarizes the source of mac...

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Hauptverfasser: KING, William, WOODELL-MAY, Jennifer E, HIGGINS, Joel C
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Methods of inducing a polarization of macrophages. The method includes obtaining a blood fraction, fractionating the blood fraction to produce a blood fraction, and contacting the blood fraction with a source of macrophages. A blood fraction including platelet-poor plasma polarizes the source of macrophages into M1 macrophages. A blood faction including a protein solution polarizes the source of macrophages into M2 macrophages.