STABLE ENZYMES BY GLYCATION REDUCTION

The present teachings provide enzymes with improved stability arising from reduced glycation. Glycation reduction can be achieved by a variety of means, including protein engineering, heating to remove background ground starch hydrolytic activity, diafiltration afiltration, and various formulation a...

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Bibliographische Detailangaben
Hauptverfasser: ORTIZ-JOHNSON, MARILIZ, GEBERT, MARK S, DALE, DOUGLAS A, DALSGAARD, SOREN, GARSKE, ADAM L
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present teachings provide enzymes with improved stability arising from reduced glycation. Glycation reduction can be achieved by a variety of means, including protein engineering, heating to remove background ground starch hydrolytic activity, diafiltration afiltration, and various formulation approaches including non-inclusion of problematic sugars, and inclusion of resistant starches.