ABUSE-DETERRENT TRANSDERMAL FORMULATIONS OF OPIATE AGONISTS AND AGONIST-ANTAGONISTS

Described herein are abuse-resistant multi-layer transdermal patches comprising opioids and opioid prodrugs having a barrier layer located between the layer containing opioid or opioid prodrug and a layer containing an opioid antagonist or opioid antagonist prodrug.

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Bibliographische Detailangaben
Hauptverfasser: LI, Guohua, GOLINSKI, Miroslaw, Jerzy, HOWARD, Jeffery, Lynn, STINCHCOMB, Audra, Lynn, BANKS, Stan Lee
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Described herein are abuse-resistant multi-layer transdermal patches comprising opioids and opioid prodrugs having a barrier layer located between the layer containing opioid or opioid prodrug and a layer containing an opioid antagonist or opioid antagonist prodrug.