Method for preparing a chitosan-based matrix comprising a fiber reinforcement member

The present invention relates to a method for preparing a chitosan-based matrix (4) comprising the following steps: - a) two separate chitosan porous layers (1, 2) obtained from lyophilisation of layers of one or more solutions of chitosan are provided, - b) the chitosan porous layers of a) are neut...

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Bibliographische Detailangaben
Hauptverfasser: Desorme, Mylène, Serrero, Aurélie
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to a method for preparing a chitosan-based matrix (4) comprising the following steps: - a) two separate chitosan porous layers (1, 2) obtained from lyophilisation of layers of one or more solutions of chitosan are provided, - b) the chitosan porous layers of a) are neutralized and washed, - c) a face (1a, 2a) of each chitosan porous layer is acidified with an acid, - d) a fiber reinforcement member (3) is provided and positioned between the two acidified faces of the two chitosan porous layers, - e) the two chitosan porous layers and the fiber reinforcement member are let to dry to obtain a matrix having the fiber reinforcement member embedded therein. The invention also relates to an implant comprising a matrix obtained according to such a method.