TRICYCLIC GYRASE INHIBITORS

TRICYCLIC GYRASE INHIBITORS

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contempl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHEN, Zhiyong, TENG, Min, LIGHTSTONE, Felice, C, TRZOSS, Michael, BORCHARDT, Allen John, LAM, Thanh To, FINN, John, ONG, Voon, ZHANG, Junhu, BENSEN, Daniel, TARI, Leslie William, LEE, Suk Joong, LI, Xiaoming, WONG, Sergio, E, PHILLIPSON, Douglas, NGUYEN, Toan, B
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.