MOLECULAR TARGETS FOR THE TREATMENT OF WOUNDS, IN PARTICULAR CHRONIC WOUNDS

MOLECULAR TARGETS FOR THE TREATMENT OF WOUNDS, IN PARTICULAR CHRONIC WOUNDS

The present invention relates to a therapeutic compound comprising: - an agent that inhibits the activity of at least one gene selected from the group consisting of MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or - an agent that enhances the activity of at leas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DUGAST-DARZACQ, Claire, SPILUTTINI HÉBERT, Béatrice, DARZACQ, Xavier, NOIZET, Maïté
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The present invention relates to a therapeutic compound comprising: - an agent that inhibits the activity of at least one gene selected from the group consisting of MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes and/or - an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds.