MOLECULAR TARGETS FOR THE PREVENTION AND/OR TREATMENT OF FIBROSIS, HYPERTROPHIC SCARS OR KELOIDS

The present invention relates to a therapeutic compound comprising : - an agent that inhibits the activity of at least one gene selected from the group consisting of FOXS1, CREB5, HIC1, IRF7, POU2F2, STAT4, TCF4, and/or - an agent that enhances the activity of at least one gene selected from the gro...

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Bibliographische Detailangaben
Hauptverfasser: DUGAST-DARZACQ, CLAIRE, NOIZET, MAÏTÉ, DARZACQ, XAVIER
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a therapeutic compound comprising : - an agent that inhibits the activity of at least one gene selected from the group consisting of FOXS1, CREB5, HIC1, IRF7, POU2F2, STAT4, TCF4, and/or - an agent that enhances the activity of at least one gene selected from the group consisting of MAF, MEOX2, SIX2 for use in the prevention and/or treatment of fibrosis, hypertrophic scar or keloid.