ANTIBODIES WITH MODIFIED ISOELECTRIC POINTS

The invention relates generally to compositions and methods for altering the isoelectric point of an antibody, and in some cases, resulting in improved plasma pharmacokinetics, e.g. increased serum half-life in vivo.

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Hauptverfasser: LAZAR, Gregory, A, DAHIYAT, Bassil, I, BERNETT, Matthew, J
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Sprache:eng ; fre ; ger
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creator LAZAR, Gregory, A
DAHIYAT, Bassil, I
BERNETT, Matthew, J
description The invention relates generally to compositions and methods for altering the isoelectric point of an antibody, and in some cases, resulting in improved plasma pharmacokinetics, e.g. increased serum half-life in vivo.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title ANTIBODIES WITH MODIFIED ISOELECTRIC POINTS
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