PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS

The present invention is directed to piperazine derivatives, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, an...

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Bibliographische Detailangaben
Hauptverfasser:	MCCAULEY, John A, DWYER, Michael P, LOUGHRAN, H. Marie, HOLLOWAY, M. Katherine, SATYANARAYANA, Tummanapalli, KEERTIKAR, Kartik M, VIJAYASARADHI, Sivalenka, ZHONG, Bin, BENNETT, David J, WADDELL, Sherman Tim, CHU, Xin-Jie, BUNGARD, Christopher J, SHEN, Dong-Ming, WILLIAMS, Peter D, CHANG, Lehua, MORRIELLO, Gregori J, SCHULZ, Jurgen, WISCOUNT, Catherine M, ZORN, Nicolas, JI, Tao, MANIKOWSKI, Jesse J, HU, Bin, SHERER, Edward C
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to piperazine derivatives, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.