AEROSOL TYROSINE KINASE INHIBITOR COMPOUNDS AND USES THEREOF

Disclosed herein are formulations of imatinib or a phenylaminopyrimidine derivative compound for aerosolization and use of such formulations for inhaled aerosol administration of imatinib or a phenylaminopyramidine derivate compound for the prevention or treatment of various fibrotic, carcinogenic,...

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Bibliographische Detailangaben
1. Verfasser: SURBER, Mark, William
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed herein are formulations of imatinib or a phenylaminopyrimidine derivative compound for aerosolization and use of such formulations for inhaled aerosol administration of imatinib or a phenylaminopyramidine derivate compound for the prevention or treatment of various fibrotic, carcinogenic, vascular and viral infectious diseases, including diseases associated with the lung, heart, kidney, liver, eye, central nervous system and surgical sites. In some embodiments, forumlations and delivery options described herein allow for efficacious local delivery of imatinib or a phenylaminopyramidine derivative compound or salt thereof.