PHAGE-BASED BACTERIAL DETECTION ASSAY

Methods of detecting target bacteria are provided. In some embodiments the methods comprise exposing the sample to a phage capable of infecting a set of target bacteria and comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments the target bacteria comprise Listeria. I...

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Hauptverfasser: BROWNELL, Daniel Robert, CAPPILLINO, Michael, THOMASON, Julie, SHIVERS, Robert Patrick, KOERIS, Michael Sandor, BOWERS, Jayson L, LU, Timothy Kuan Ta, KRZYMANSKA-OLEJNIK, Edyta
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Methods of detecting target bacteria are provided. In some embodiments the methods comprise exposing the sample to a phage capable of infecting a set of target bacteria and comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments the target bacteria comprise Listeria. In some embodiments the target bacteria are all Listeria. Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.