CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACIDS

Esterified cellulose ethers comprising groups of formula -C(O)-CHR′-CHR″-COOA, wherein, R′ and R″ are hydrogen or (-S)m(-R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A...

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Bibliographische Detailangaben
Hauptverfasser:	HILLMYER, Marc A, SCHMITT, Robert L, GUILLAUDEU, Steven J, YIN, Ligeng
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	Esterified cellulose ethers comprising groups of formula -C(O)-CHR′-CHR″-COOA, wherein, R′ and R″ are hydrogen or (-S)m(-R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′-CHR″ one of R′ and R″ is hydrogen and the other one is (-S)m(-R1)n-R2, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.