CELL SORTING METHOD

Provided is a pluripotent stem cell-derived differentiated cell with a reduced tumor risk. A method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells, including contacting a pigment epitheli...

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Bibliographische Detailangaben
Hauptverfasser:	KAWAMATA, Shin, GO, Masahiro, NISHISHITA, Naoki, KANEMURA, Hoshimi
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided is a pluripotent stem cell-derived differentiated cell with a reduced tumor risk. A method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells, including contacting a pigment epithelium-derived factor with the differentiated cell population to induce apoptosis of the undifferentiated cells. An agent for cell transplantation therapy, containing a differentiated cell population substantially free of an undifferentiated cell, which is obtained by the method. An agent for inducing apoptosis of an undifferentiated cell, containing a pigment epithelium-derived factor. Combined use of the aforementioned agent for cell transplantation therapy and the aforementioned agent for inducing apoptosis.