METHOD FOR PRODUCING GLYCOLIDE

A method for producing a GL comprising: (I) a heating step of heating a mixture either under normal pressure or reduced pressure at a temperature at which a polyglycolic acid (PGA) undergoes depolymerization, the mixture containing the PGA and a polyethylene glycol ether which is represented by the...

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Bibliographische Detailangaben
Hauptverfasser: IKEYAMA, YOSHIKO, YAMANE, KAZUYUKI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method for producing a GL comprising: (I) a heating step of heating a mixture either under normal pressure or reduced pressure at a temperature at which a polyglycolic acid (PGA) undergoes depolymerization, the mixture containing the PGA and a polyethylene glycol ether which is represented by the formula: X-O-(-CH 2 CH 2 -O-) p -Y (wherein X and Y are each independently an alkyl group or an aryl group having from 2 to 20 carbon atoms, and p is an integer from 1 to 5) and which has a molecular weight of from 150 to 450 and a boiling point of from 130 to 220°C at a pressure of 3 kPa; (II) a solution-forming step in which the mixture is rendered in a solution state in which a melt phase of the PGA and a liquid phase consisting of the polyethylene glycol ether essentially form a uniform phase; (III) a GL production step in which a glycolide (GL) is produced by a depolymerization reaction of the PGA by continuing to heat the mixture in the solution state; (IV) a distillation step of distilling off the produced GL together with the polyethylene glycol ether (B) from the depolymerization reaction system; and (V) a recovery step of recovering the GL from the distillate.