CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser:	TORRES, Luis, DU, Xiaoxing, CHILDERS, Matthew Lloyd, GUERIN, David, ZHANG, Hongjun, FULLER, Peter, BRUBAKER, Jason, KATZ, Jason David, ZENG, Hongbo, CAI, Jiaqiang, ZHENG, Zhixiang, SCOTT, Mark E, THOMPSON, Christopher F, FALCONE, Danielle, KONG, Norman, BAI, Yunfeng, PU, Qinglin, LIU, Yumei, DINSMORE, Christopher, WANG, Chonggang
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.