MARKERS FOR ISOCITRATE DEHYDROGENASE INHIBITORS

The invention provides methods of detecting cancer and detecting activity of IDH inhibitors, and methods of screening for IDH inhibitors by detecting levels of H3K9me2.

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Bibliographische Detailangaben
Hauptverfasser:	SAENZ-VASH, VERONICA, LIN, FALLON, SHEBANOVA, OLGA, MEYER, RONALD, ZHAI, HUILI, CHO, YOUNG SHIN, MCLAUGHLIN, MARGARET ELISE, PAGLIARINI, RAYMOND, LEVELL, JULIAN ROY
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides methods of detecting cancer and detecting activity of IDH inhibitors, and methods of screening for IDH inhibitors by detecting levels of H3K9me2.