ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural com...

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Bibliographische Detailangaben
Hauptverfasser: WOOD, Monika, BINKOWSKI, Brock, F, SCHWINN, Marie, NATH, Nidhi, DART, Melanie, KIRKLAND, Thomas, WOOD, Keith, ZEGZOUTI, Hicham, ROBERS, Matthew, UNCH, James, MEISENHEIMER, Poncho, MACHLEIDT, Thomas, PULUKKUNAT, Dileep, K, HALL, Mary, GOUELI, Said, MONDAL, Subhanjan, DIXON, Andrew, S, ENCELL, Lance
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.