METHODS OF INCREASING PROTEIN PURITY USING PROTEIN A BASED CHROMATOGRAPHY

The present invention provides methods for increasing purity of an Fc-containing protein by removing protein aggregates during the Protein A chromatography step used during the purification of the Fc-containing protein.

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Bibliographische Detailangaben
Hauptverfasser: BIAN, Nanying, HOLSTEIN, Melissa
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention provides methods for increasing purity of an Fc-containing protein by removing protein aggregates during the Protein A chromatography step used during the purification of the Fc-containing protein.