An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate

An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate

The present invention relates to a pharmaceutical composition for oral use comprising a mixture of ibuprofen and ibuprofen sodium dihydrate, pseudoephedrine hydrochloride, and chlorpheniramine maleate in an acceptable carrier wherein the weight ratio of ibuprofen to ibuprofen sodium dihydrate as fre...

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Hauptverfasser: Öztuna, Banu, Kanik, Bayram, Öner, Levent, Aksoy, Ediz, Ünver, Levent
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Öztuna, Banu
Kanik, Bayram
Öner, Levent
Aksoy, Ediz
Ünver, Levent
description The present invention relates to a pharmaceutical composition for oral use comprising a mixture of ibuprofen and ibuprofen sodium dihydrate, pseudoephedrine hydrochloride, and chlorpheniramine maleate in an acceptable carrier wherein the weight ratio of ibuprofen to ibuprofen sodium dihydrate as free acid equivalent is 19:1 to 1:19 and more than 15% of total ibuprofen dissolves in 15 minutes in 900 ml of 0.1 N HCl solution at pH 1.2 at 37°C using USP Type II (paddle) apparatus rotating at 50 RPM.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate
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