BIOREACTOR USING ACOUSTIC STANDING WAVES

BIOREACTOR USING ACOUSTIC STANDING WAVES

A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DIONNE, Jason, PRESZ, Walter M. jr, MASI, Louis, KOWALSKI III, Stanley, LIPKENS, Bart, DUTRA, Brian, MERCADO, Ari, KENNEDY III, Thomas, MARTIN, Arthur
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
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Beschreibung
Zusammenfassung:A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor. The bioreactor includes a reaction vessel, an agitator, a feed inlet, and an outlet. A filtering device is included that has an inlet, a flow chamber and a sleeve surrounding the flow chamber, where the sleeve includes the ultrasonic transducer.