PROCESS FOR PREPARING MEROPENEM TRIHYDRATE

PROCESS FOR PREPARING MEROPENEM TRIHYDRATE

Provided is a process for the preparation of meropenem trihydrate in high purity and high yield, including using a dry methanol solvate of meropenem, which can remarkably reduce the amount of residual solvents in the resulting product, thereby obtain meropenem trihydrate in high purity.

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Bibliographische Detailangaben
Hauptverfasser: LIM, BYUNG-JO, CHOI, SOO-JIN, PARK, SUNG-WOO, YOON, HEE-KYOON, LEE, KYUNG-HO, LEE, BYUNG-GOO, JUN, SUN-AH
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided is a process for the preparation of meropenem trihydrate in high purity and high yield, including using a dry methanol solvate of meropenem, which can remarkably reduce the amount of residual solvents in the resulting product, thereby obtain meropenem trihydrate in high purity.