SUBSTITUTED PYRROLOPYRIMIDINES AS HDM2 INHIBITORS

The present invention provides substituted pyrrolopyrimidines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and pot...

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Bibliographische Detailangaben
Hauptverfasser:	KUDALE, Amit Ashokrao, VOSS, Matthew, E, BOGEN, Stephane, L, FRADERA LLINAS, Francesc Xavier, DOLL, Ronald, J, DINSMORE, Christopher, THOMPSON, Christopher Francis, REUTERSHAN, Michael Hale, YANG, Liping, ALTMAN, Michael, D
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides substituted pyrrolopyrimidines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.