PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser: MCGOWAN, Meredeth, DENG, Yongqi, ACHAB, Abdelghani Abe, FONG, Kin Chiu, MU, Changwei, LENG, Xiansheng, ZHANG, Rong, KATZ, Jason D, METHOT, Joey L, CHRISTOPHER, Matthew P, ANTHONY, Neville John, ZHANG, Sixing, ZHOU, Hua, KATTAR, Solomon, FRADERA LLINAS, Francesc Xavier, GARCIA, Yudith, ALTMAN, Michael D, GUZI, Timothy
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.