NOVEL COMPOUNDS THAT ARE ERK INHIBITORS

Disclosed are the ERK inhibitors of formula (1.0), having a pyrazolopyridine base structure, and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0).

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Bibliographische Detailangaben
Hauptverfasser: TANG, Shuyi, LIPFORD, Kathryn, BOYCE, Christopher, RICHARD, Judson, E, KARUNAKARAN, Ganesh Babu, DANIELS, Matthew, H, KOZLOWSKI, Joseph, FERGUSON, Ron, SILIPHAIVANH, Phieng, WILSON, Kevin, J, ANGELES, Angie, R, HUANG, Xianhai, FEVRIER, Salem, ZHOU, Wei, SLOMAN, David, WHITE, Catherine, FALCONE, Danielle, BAKSHI, Raman Kumar, WITTER, David, J, O'BOYLE, Brendan, KURUKULASURIYA, Ravi, MANSOOR, Umar Faruk
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed are the ERK inhibitors of formula (1.0), having a pyrazolopyridine base structure, and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0).