METHOD OF TREATMENT OR PROPHYLAXIS OF INFECTIONS OF THE EYE

A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that includes a dendrimer of 1 to 8 generations with one or more sulfonic acid- or sulfonate-containing moie...

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Bibliographische Detailangaben
Hauptverfasser: BARRETT, COLIN, PAUL, FAIRLEY, JACINTH, KINCAID, PAULL, JEREMY, ROBERT ARTHUR
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that includes a dendrimer of 1 to 8 generations with one or more sulfonic acid- or sulfonate-containing moieties attached to one or more surface groups of the outermost generation of the dendrimer. Compositions containing the macromolecule or salt are useful in these methods.