METHOD, COMBINATION AND/OR COMPOSITION FOR INDUCING CARDIOMYOCYTE DIFFERENTATION

The present invention relates to a method for inducing cardiomyocyte differentiation using a combination and/or composition of factors. The present invention also includes the combination and/or composition of factors. For example, the factors comprise at least one p38-MAPK modulator, at least one i...

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Bibliographische Detailangaben
Hauptverfasser: SEQUIERA, GLEN LESTER, SHIM, SE NGIE, WINSTON, MEHTA, ASHISH
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a method for inducing cardiomyocyte differentiation using a combination and/or composition of factors. The present invention also includes the combination and/or composition of factors. For example, the factors comprise at least one p38-MAPK modulator, at least one immunomodulator, at least one Wnt modulator and/or at least one ROS modulator. In particular, the factors comprise at least one p38-MAPK inhibitor, at least one immunosuppressant, at least one Wnt modulator and/or at least one ROS activator.