SUBSTITUTED PYRIDINE SPLEEN TYROSINE KINASE (Syk) INHIBITORS

The invention provides certain substituted pyridines of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, Cy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds fo...

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Hauptverfasser: SCHELL, ADAM, J, TAOKA, BRANDON, M, KNOWLES, SANDRA LEE, ALTMAN, MICHAEL, D, JEWELL, JAMES, P, ELLIS, JOHN, MICHAEL, DESCHENES, DENIS, NORTHHRUP, ALAN, B, ROBICHAUD, JOEL, REUTERSHAN, MICHAEL, H, FISCHER, CHRISTIAN, HAIDLE, ANDREW, M, CHRISTOPHER, MATTHEW, KATTAR, SOLOMON, D, ZHOU, HUA, BURCH, JASON, DONOFRIO, ANTHONY, BLOUIN, MARC
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention provides certain substituted pyridines of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, Cy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.