BETA-GLUCAN IMMUNOTHERAPEUTIC METHODS

This disclosure describes, in one aspect, a method for identifying ²-glucan binding to immune cells of a subject. Generally, the method includes obtaining a blood sample from the subject, the blood sample comprising immune cells, adding soluble ²-glucan to at least a portion of the blood sample and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	DANIELSON, MICHAEL, E, BOSE, NANDITA, WALSH, RICHARD, M, NELSON, MARIANA, I, ANTONYSAMY, MARY, A, MICHEL, KYLE, S, GROSSMAN, WILLIAM, J
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This disclosure describes, in one aspect, a method for identifying ²-glucan binding to immune cells of a subject. Generally, the method includes obtaining a blood sample from the subject, the blood sample comprising immune cells, adding soluble ²-glucan to at least a portion of the blood sample and incubating the mixture under conditions allowing the soluble ²-glucan to bind to the immune cells, and detecting soluble ²-glucan bound to the immune cells. In another aspect, the disclosure describes a method that generally includes identifying the subject as a low binder of ²-glucan, and co-administering to the subject a soluble ²-glucan and an antibody preparation capable of converting the subject from a low binder to a high binder.