Pegylated amyloid beta fab

A method to treat conditions associated with A² peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A² peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached...

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Bibliographische Detailangaben
Hauptverfasser:	CHOW, CHI-KIN, KUCHIBHOTLA, UMA, HANSEN, RYAN JOHN, LU, JIRONG, MCDONNELL, PETER COLON, BALES, KELLY RENEE, BUMOL, THOMAS FRANK, DEMATTOS, RONALD BRADLEY
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method to treat conditions associated with A² peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A² peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.