THERAPY FOR KIDNEY DISEASE AND/OR HEART FAILURE BY INTRADERMAL INFUSION

Intradermal delivery devices, systems and methods thereof for the administration of a natriuretic or chimeric peptide are described. The described delivery devices, systems and methods provide for the treatment of pathological conditions such as kidney disease alone, heart failure alone, concomitant...

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Hauptverfasser: WIENEKE, CHAD, A, KAYTOR, MIKE, GROVENDER, ERIC, VAN ANTWERP, WILLIAM, J.L, DONOVAN, MAURA
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creator WIENEKE, CHAD, A
KAYTOR, MIKE
GROVENDER, ERIC
VAN ANTWERP, WILLIAM, J.L
DONOVAN, MAURA
description Intradermal delivery devices, systems and methods thereof for the administration of a natriuretic or chimeric peptide are described. The described delivery devices, systems and methods provide for the treatment of pathological conditions such as kidney disease alone, heart failure alone, concomitant kidney disease and heart failure, or cardiorenal syndrome by delivery of a natriuretic or chimeric peptide through a microneedle array using a delivery pump. The described delivery devices, systems and methods can provide for greater availability of a natriuretic or chimeric peptide and improved pharmacokinetics.
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subjects CHEMISTRY
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title THERAPY FOR KIDNEY DISEASE AND/OR HEART FAILURE BY INTRADERMAL INFUSION
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