THERAPY FOR KIDNEY DISEASE AND/OR HEART FAILURE BY INTRADERMAL INFUSION

Intradermal delivery devices, systems and methods thereof for the administration of a natriuretic or chimeric peptide are described. The described delivery devices, systems and methods provide for the treatment of pathological conditions such as kidney disease alone, heart failure alone, concomitant...

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Bibliographische Detailangaben
Hauptverfasser: WIENEKE, CHAD, A, KAYTOR, MIKE, GROVENDER, ERIC, VAN ANTWERP, WILLIAM, J.L, DONOVAN, MAURA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Intradermal delivery devices, systems and methods thereof for the administration of a natriuretic or chimeric peptide are described. The described delivery devices, systems and methods provide for the treatment of pathological conditions such as kidney disease alone, heart failure alone, concomitant kidney disease and heart failure, or cardiorenal syndrome by delivery of a natriuretic or chimeric peptide through a microneedle array using a delivery pump. The described delivery devices, systems and methods can provide for greater availability of a natriuretic or chimeric peptide and improved pharmacokinetics.