NEURONAL CULTURE MEDIUM AND METHOD FOR PRODUCING IN VIVO-LIKE AND ENHANCED SYNAPTOGENESIS NEURON MODEL

An object of the present invention is to develop and provide a method for producing a neuron model having reproduced in vivo properties by improving a cell culture medium composition and a cell culture medium composition necessary for the production of such neuron model. According to the present inv...

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Bibliographische Detailangaben
Hauptverfasser: TAKAHASHI, TOMOYUKI, GUILLAUD, LAURENT ELIE, DIMITROV, DIMITAR IVANOV, TAOUFIQ, ZACHARIE MEHDI FRANCOIS
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An object of the present invention is to develop and provide a method for producing a neuron model having reproduced in vivo properties by improving a cell culture medium composition and a cell culture medium composition necessary for the production of such neuron model. According to the present invention, cell culture is carried out in vitro using a medium for producing in vivo-like and enhanced synaptogenesis neuron model supplemented with a medium supplement for producing in vivo-like and enhanced synaptogenesis neuron model comprising any or any combination of NT-3, potassium or a salt thereof, and FGF2.