PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS

The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.

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Bibliographische Detailangaben
Hauptverfasser: CLEATOR, EDWARD, KUO, SHENUN, YASUDA, NOBUYOSHI, YIN, JIANGUO, BELYK, KEVIN, M, XIANG, BANGPING, MALIGRES, PETER, EMMANUEL
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.