PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Bibliographische Detailangaben
Hauptverfasser: Trudeau, Martin, Neubert-Langille, Bobbiana, Grootenhuis, Peter D.J, Van Groor, Frederick F, Zlokarnik, Gregor, Krueger, Brian R, Looker, Adam R, Roper, Stefanie, Ryan, Michael, Yap, Dahrika Milfred Lao, Demattei, John, Botfield, Martyn C
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.