PROCESSES FOR DELIVERY OF VISCOUS DRUG THERAPIES

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high- viscosity fluid. This allows the use of pro - t...

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Bibliographische Detailangaben
Hauptverfasser:	HEINTZ, AMY, M, RISSER, STEVEN, M, BLUM, TIMOTHY, M, SCRIBBEN, ERIC, C, ELLIS, JEFFREY, L, CLAY, JOHN, D
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE
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Beschreibung
Zusammenfassung:	Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high- viscosity fluid. This allows the use of pro - tein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.