THERAPEUTIC SULFATED POLYSACCHARIDES, COMPOSITIONS THEREOF, AND METHODS FOR TREATING PATIENTS

Methods are disclosed for screening sulfated polysaccharides to identify one or more therapeutic agents that can be used for the treatment of a variety of disorders that affect the glycocalyx of a subject. A glycocalyx disease inhibitor identified by the method may increase the production of heparin...

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1. Verfasser: DANIELS, BRUCE A
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Methods are disclosed for screening sulfated polysaccharides to identify one or more therapeutic agents that can be used for the treatment of a variety of disorders that affect the glycocalyx of a subject. A glycocalyx disease inhibitor identified by the method may increase the production of heparin sulfate or of one or more heparin sulfate proteins in the glycocalyx of at least one endothelial or other vascular cell.