PYRROLOPYRAZINE KINASE INHIBITORS
The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
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| creator | LOVEY, Allen John O'YANG, Counde LYNCH, Stephen M LUK, Kin-Chun Thomas HERMANN, Johannes Cornelius DE VICENTE FIDALGO, Javier KENNEDY-SMITH, Joshua CHEN, Shaoqing LUCAS, Matthew C SCHOENFELD, Ryan Craig PADILLA, Fernando SIDDURI, Achyutharao HAMILTON, Matthew Michael WOVKULICH, Peter Michael LI, Hongju SOTH, Michael WANG, Ce ZHANG, Xiaohu |
| description | The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PYRROLOPYRAZINE KINASE INHIBITORS |
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