PYRROLOPYRAZINE KINASE INHIBITORS

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.

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Bibliographische Detailangaben
Hauptverfasser:	LOVEY, Allen John, O'YANG, Counde, LYNCH, Stephen M, LUK, Kin-Chun Thomas, HERMANN, Johannes Cornelius, DE VICENTE FIDALGO, Javier, KENNEDY-SMITH, Joshua, CHEN, Shaoqing, LUCAS, Matthew C, SCHOENFELD, Ryan Craig, PADILLA, Fernando, SIDDURI, Achyutharao, HAMILTON, Matthew Michael, WOVKULICH, Peter Michael, LI, Hongju, SOTH, Michael, WANG, Ce, ZHANG, Xiaohu
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.