PRODUCTION METHOD FOR 4, 4-DIFLUORO-3,4-DIHYDROISOQUINOLINE DERIVATIVE

PRODUCTION METHOD FOR 4, 4-DIFLUORO-3,4-DIHYDROISOQUINOLINE DERIVATIVE

Provided is a simple and efficient method for the large-scale production of a 4,4-difluoro-3,4-dihydroisoquinoline derivative. In the method for producing a 4,4-difluoro-3,4-dihydroisoquinoline derivative represented by general formula (1): a compound represented by general formula (2): is reacted w...

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Bibliographische Detailangaben
Hauptverfasser: KAJINO, FUMIE, UMETANI, HIDEKI, KONDO, NOBUHIRO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided is a simple and efficient method for the large-scale production of a 4,4-difluoro-3,4-dihydroisoquinoline derivative. In the method for producing a 4,4-difluoro-3,4-dihydroisoquinoline derivative represented by general formula (1): a compound represented by general formula (2): is reacted with hydrogen fluoride.