DIAGNOSTIC METHYLATION MARKERS OF EPITHELIAL OR MESENCHYMAL PHENOTYPE AND RESPONSE TO EGFR KINASE INHIBITOR IN TUMOURS OR TUMOUR CELLS

The present invention provides methods for determining epithelial and mesenchymal phenotype of tumors and predicting whether tumor growth will be sensitive or resistant to treatment with an EGFR inhibitor.

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Bibliographische Detailangaben
Hauptverfasser: WALTER, KIMBERLY, HOLCOMB, THOMAS M, SHAMES, DAVID
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides methods for determining epithelial and mesenchymal phenotype of tumors and predicting whether tumor growth will be sensitive or resistant to treatment with an EGFR inhibitor.