NOVEL METHOD FOR DIAGNOSIS OF HIGH-AFFINITY BINDERS AND MARKER SEQUENCES

The present invention relates to a novel method for diagnosing high-affinity binders, in particular antibodies or autoantibodies, and the identification, characterization and selection of marker sequences and diagnostic use thereof, in particular in the form of a panel. The invention also relates to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LÜKING, ANGELIKA, MÜLLNER, STEFAN, SCHWERMANN, JESSICA, GÖHLER, HEIKE, SCHULZ-KNAPPE, PETER
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to a novel method for diagnosing high-affinity binders, in particular antibodies or autoantibodies, and the identification, characterization and selection of marker sequences and diagnostic use thereof, in particular in the form of a panel. The invention also relates to a singleplex assay in which the discovered selection of marker sequences is used in the form of a panel and high-affinity binders are detected using a single signal.