MICROFLUIDIC DRUG DELIVERY DEVICES

A microfluidic convection-enhanced-delivery (CED) device, comprising:a shank portion (14) on a support scaffold (12);a fluid delivery conduit (416) having an inlet port and a plurality of outlet ports (428), the delivery conduit formed in or on the shank portion and comprising first and second upstr...

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Bibliographische Detailangaben
Hauptverfasser: SINGH, Deep, Arjun, ANAND, Pj
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A microfluidic convection-enhanced-delivery (CED) device, comprising:a shank portion (14) on a support scaffold (12);a fluid delivery conduit (416) having an inlet port and a plurality of outlet ports (428), the delivery conduit formed in or on the shank portion and comprising first and second upstream lumens (434, 436) and a single downstream lumen (438);a flow restriction formed within the conduit at a merge of the first and second upstream lumens into the single downstream lumen, the flow restriction being configured to adjust a pressure of fluid being directed through the at least one fluid delivery conduit;wherein the flow restriction comprises a constricted region of the at least one fluid delivery conduit;wherein the plurality of outlet ports (428) are formed in the upstream lumens and in the single downstream lumen respectively and are formed in an outermost surface of the microfluidic CED device.