PROCESS FOR PRODUCING ORTHOMYXOVIRAL ANTIGEN AND VACCINES

The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the vol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAN 'T HOF, RON, SHAKER, SABAH, CUI, YI-QING, VAN ROOIJ, GEERTJE JACOBA, THUS, JO, WANG, YIDING
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the volume of the obtained liquid harvest, solubilizing the enveloped virus, and purifying viral antigen. The present invention further refers to the use of said method for the production of a vaccine preparation.