3- OR 5-BIPHENYL-4-YLISOXAZOLE-BASED COMPOUNDS USEFUL FOR THE TREATMENT OF FIBROSIS, PAIN , CANCER AND RESPIRATORY, ALLERGIC, NERVOUS SYSTEM OR CARDIOVASCULAR DISORDERS

3- OR 5-BIPHENYL-4-YLISOXAZOLE-BASED COMPOUNDS USEFUL FOR THE TREATMENT OF FIBROSIS, PAIN , CANCER AND RESPIRATORY, ALLERGIC, NERVOUS SYSTEM OR CARDIOVASCULAR DISORDERS

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating L...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SEIDERS, THOMAS, JON, ROPPE, JEFFREY, ROGER, PARR, TIMOTHY, ANDREW
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.